Standard Treatment  Removal of liver metastases may be done in selected cases. The five-year survival rate for patients with solitary metastases exceeds 20 percent. The chances for cure are improved when there are only two or three metastases to be removed. Non-curative removal provides no benefits to patients who have no symptoms, since survival is not affected. Both palliative radiation therapy and palliative chemotherapy may be given for recurrent disease.

Investigational 
• Biologic therapy with 5-FU + interferon, monoclonal antibodies or interleukin-2.
• 5-FU + PALA, Phase I and II agents.